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Spirochoeta pallida (de la syphilis) (1910)
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Overview:
Jean Comandon, pioneer of microcinematography, recorded this time-lapse film in c. 1910, using a ultramicroscope. The film show living spiral shaped syphilis bacteria moving among red blood cells of frog. Notice the back-and-forth movement, characterizing the disease-causing form. (Wikipedia)
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